Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577112 | 0.85 | HDAC6 (0.34) | MAPTRXFP1LRRK2 | |
| SCHEMBL24577155 | 0.85 | IKBKE (0.34) | MAPTRXFP1LMNA | |
| SCHEMBL24577132 | 0.84 | NAMPT (0.38) | MAPTRXFP1 | |
| SCHEMBL24578879 | 0.81 | PDE3B (0.33) | — | |
| SCHEMBL24577143 | 0.80 | KMT2A (0.33) | — | |
| SCHEMBL24578874 | 0.80 | IKBKE (0.40) | — | |
| SCHEMBL24577174 | 0.79 | IKBKE (0.38) | — | |
| SCHEMBL24579014 | 0.78 | — | — | |
| SCHEMBL24577786 | 0.77 | IKBKE (0.34) | — | |
| SCHEMBL24577200 | 0.76 | HDAC6 (0.33) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |