SCHEMBL2457764

SCHEMBL2457764

C=CCc1cc(O)c(CC=C)c(CC=C)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
POLB P06746 2/20 0.39
XDH P47989 2/20 0.37
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
GAA P10253 2/20 0.36
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
AKR1B1 P15121 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH2 P05091 1/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALOX5 P09917 2/20 0.36
GABRB1 P18505 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245217 0.82 GABRA1 (0.48) GABRA1GABRB2POLBXDHMEN1
SCHEMBL11033561 0.80 GABRA1 (0.47) GABRA1GABRB2POLBXDHMEN1
SCHEMBL3045553 0.80 GABRA1 (0.47) GABRA1GABRB2POLBXDHMEN1
SCHEMBL27592056 0.76 GABRA1 (0.47) GABRA1GABRB2POLBXDHMEN1
SCHEMBL1420694 0.74 GABRA1 (0.64) GABRA1GABRB2POLBXDHMEN1
SCHEMBL1744767 0.74 GABRA1 (0.58) GABRA1GABRB2POLBXDHMEN1
SCHEMBL22493000 0.73 GABRA1 (0.40) GABRA1GABRB2POLBXDHMEN1
SCHEMBL790696 0.73 GABRA1 (0.41) GABRA1GABRB2POLBXDHMEN1
SCHEMBL15389161 0.72 GABRA1 (0.47) GABRA1GABRB2POLBXDHMEN1
SCHEMBL10981064 0.72 GABRA1 (0.47) GABRA1GABRB2POLBXDHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179849-B2 Antimicrobial compositions containing colloids of oligodynamic metals C. R. BARD, INC. (US) 2007-02-20 US claimed
EP-2948256-B1 ANTISEPTIC APPLICATOR CAREFUSION 2200 INC (US) 2022-12-14 EP disclosed
EP-2173428-B1 FOLEY CATHETER HAVING STERILE BARRIER BARD INC C R (US) 2018-10-10 EP disclosed
CN-103338732-B Feminine care absorbent article for use in warm climates 金伯利-克拉克环球有限公司 2016-08-10 CN disclosed
EP-2948256-A1 ANTISEPTIC APPLICATOR CareFusion 2200 Inc. (US) 2015-12-02 EP disclosed
US-9119946-B2 Antiseptic applicator CAREFUSION 2200, INC. (US) 2015-09-01 US disclosed
US-9084838-B2 Feminine care absorbent article for use in warm climates KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-07-21 US disclosed
WO-2014116482-A1 ANTISEPTIC APPLICATOR CAREFUSION 2200, INC. (US) 2014-07-31 WO disclosed
US-20140205360-A1 ANTISEPTIC APPLICATOR CAREFUSION 2200, INC. (US) 2014-07-24 US disclosed
CN-103338732-A Feminine care absorbent article for use in warm climates KIMBERLY CLARK CO 2013-10-02 CN disclosed
US-20070048345-A1 Antimicrobial composition KIMBERLY-CLARK WORLDWIDE, INC. 2007-03-01 US disclosed
US-7179849-B2 Antimicrobial compositions containing colloids of oligodynamic metals C. R. BARD, INC. (US) 2007-02-20 US disclosed
CN-1895672-A Multifunctional broad-spectrum obtundent of polyphyletic synergistic and its use LINXIANG BIOLOG TECHNOLOGY CO (CN) 2007-01-17 CN disclosed
CN-1623394-A Multielement syneryistic multifunction broad spectrum disinfectant and its application HONG LIN (CN) 2005-06-08 CN disclosed
US-20050042266-A1 Cyanoacrylate compositions containing anti-microbial agent CLOSURE MEDICAL CORPORATION (US) 2005-02-24 US disclosed
EP-1508601-A1 Cyanoacrylate compositions containing anti-microbial agent Closure Medical Corporation (US) 2005-02-23 EP disclosed
US-20040116551-A1 Antimicrobial compositions containing colloids of oligodynamic metals C.R. BARD, INC. 2004-06-17 US disclosed
WO-2004017738-A1 ANTIMICROBIAL COMPOSITIONS CONTAINING COLLOIDS OF OLIGODYNAMIC METALS C.R. BARD, INC. (US) 2004-03-04 WO disclosed
US-6503952-B2 Mixture of chlorhexidine, quaternary ammonium salt and chlorinated phenol THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2003-01-07 US disclosed
US-20010016589-A1 Mixture of chlorhexidine, quaternary ammonium salt and chlorinated phenol TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2001-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048345-A1 Antimicrobial composition MGAM, CUTA, CD68 GABRA1 3280/4885GABRB2 3006/4885POLB 1632/4885
US-20050042266-A1 Cyanoacrylate compositions containing anti-microbial agent CLSPN, PCNA, CDC73 GABRA1 2131/4885GABRB2 2999/4885POLB 447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.