Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24579735 | 0.83 | HDAC7 (0.57) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24579574 | 0.83 | HDAC1 (0.65) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24578163 | 0.81 | HDAC7 (0.56) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24578148 | 0.80 | HDAC7 (0.53) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24578110 | 0.80 | HDAC7 (0.54) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24578115 | 0.80 | HDAC7 (0.53) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24579636 | 0.76 | HDAC7 (0.58) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24577966 | 0.76 | HDAC7 (0.61) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24579577 | 0.75 | HDAC7 (0.67) | HDAC7HDAC1HDAC6HDAC8HDAC9 | |
| SCHEMBL24577976 | 0.75 | HDAC7 (1.00) | HDAC7HDAC1HDAC6HDAC8HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |