Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.67 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24579645 | 0.85 | PLA2G2A (0.48) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24579572 | 0.81 | HDAC7 (0.61) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24577976 | 0.80 | HDAC7 (1.00) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24579636 | 0.79 | HDAC7 (0.58) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24577966 | 0.77 | HDAC7 (0.61) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24578125 | 0.77 | HDAC7 (0.58) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL29775271 | 0.76 | HDAC7 (0.71) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24577958 | 0.75 | HDAC7 (0.59) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24578144 | 0.75 | HDAC1 (0.62) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL27188652 | 0.74 | HDAC7 (0.68) | HDAC7HDAC1HDAC4HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |