Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 7/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 4/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 1.00 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 1.00 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975467 | 0.85 | HDAC7 (0.72) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24579577 | 0.80 | HDAC7 (0.67) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24579576 | 0.79 | HDAC7 (0.66) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL29775271 | 0.78 | HDAC7 (0.71) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL13845079 | 0.78 | HDAC7 (0.62) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24578029 | 0.77 | HDAC7 (0.62) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24578144 | 0.77 | HDAC1 (0.62) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL916482 | 0.76 | HDAC1 (1.00) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24577966 | 0.76 | HDAC7 (0.61) | HDAC7HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL24579572 | 0.76 | HDAC7 (0.61) | HDAC7HDAC1HDAC4HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |