SCHEMBL245808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12440185	0.92	TGFBR1 (0.41)	TGFBR1PRKD3PRKD1PRKD2CYP3A4
	SCHEMBL244421	0.89	KDR (0.47)	TGFBR1PRKD3PRKD1PRKD2CYP3A4
	SCHEMBL245961	0.88	TGFBR1 (0.39)	TGFBR1CYP17A1PRKD3PRKD1PRKD2
	SCHEMBL12440277	0.83	RPS6KA3 (0.43)	TGFBR1PRKD3PRKD1PRKD2CYP3A4
	SCHEMBL2328148	0.83	GRM2 (0.45)	CYP11B2CYP11B1TGFBR1CYP17A1CYP3A4
	SCHEMBL2321937	0.83	MAPK1 (0.40)	CYP11B2CYP11B1TGFBR1IDO1F2
	SCHEMBL2324131	0.82	IDO1 (0.40)	CYP11B2CYP11B1TGFBR1PRKD3PRKD1
	SCHEMBL12440747	0.82	CYP2A6 (0.39)	CYP11B2CYP11B1TGFBR1PRKD3PRKD1
	SCHEMBL3390023	0.82	TGFBR1 (0.40)	TGFBR1PRKD3PRKD1PRKD2CYP3A4
	SCHEMBL247583	0.81	NPC1 (0.44)	CYP11B2CYP11B1TGFBR1CYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.