SCHEMBL2458294

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2463173	0.95	CHRM1 (0.42)	CHRM1CASP3SENP8SENP7SENP6
	SCHEMBL2492610	0.91	CHRM1 (0.40)	CHRM1CASP3SENP8SENP7SENP6
	SCHEMBL2584779	0.91	CHRM1 (0.39)	CHRM1CASP3SENP8SENP7SENP6
	SCHEMBL2581807	0.91	CHRM1 (0.45)	CHRM1FFAR1FFAR4PTGDR2GFER
	SCHEMBL2489841	0.91	CHRM1 (0.39)	CHRM1PTGDR2KDM4EALDH1A1HSD17B10
	Hydrochloric Acid SCHEMBL13560351	0.90	CHRM1 (0.39)	CHRM1PTGDR2KDM4EALDH1A1HSD17B10
	SCHEMBL15472265	0.88	CHRM1 (0.43)	CHRM1PTGDR2GAAKDM4EMEN1
	SCHEMBL2495645	0.88	CHRM1 (0.41)	CHRM1PTGDR2KDM4EALDH1A1HSD17B10
	SCHEMBL2493908	0.88	CHRM1 (0.39)	CHRM1PTGDR2KDM4EALDH1A1HSD17B10
	SCHEMBL1136185	0.87	CHRM1 (0.41)	CHRM1PTGDR2KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.