SCHEMBL2584779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2586715	0.93	CHRM1 (0.37)	CHRM1KEAP1NFE2L2CLK1RAB9A
	SCHEMBL2458294	0.91	CHRM1 (0.43)	CHRM1KEAP1NFE2L2FFAR1FFAR4
	SCHEMBL2490834	0.90	CHRM1 (0.36)	CHRM1KEAP1NFE2L2CLK1RAB9A
	SCHEMBL2463173	0.89	CHRM1 (0.42)	CHRM1FFAR1FFAR4CLK1RAB9A
	SCHEMBL2489724	0.89	MAPT (0.37)	CHRM1KEAP1NFE2L2KDM4EMEN1
	SCHEMBL2535340	0.88	CHRM1 (0.34)	CHRM1CLK1RAB9AGFERCNR1
	SCHEMBL15474182	0.87	CHRM1 (0.35)	CHRM1CLK1RAB9ACNR1CNR2
	SCHEMBL2492610	0.86	CHRM1 (0.40)	CHRM1KEAP1NFE2L2FFAR1FFAR4
	SCHEMBL2581807	0.85	CHRM1 (0.45)	CHRM1KEAP1NFE2L2FFAR1FFAR4
	SCHEMBL7900961	0.84	HTR1A (0.40)	KDM4EMEN1USP2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.