SCHEMBL24586992

SCHEMBL24586992

O=C(OCCCCCBr)OCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
EPHX2 P34913 13/20 0.40
GBA2 Q9HCG7 1/20 0.38
GBA1 P04062 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24587719 1.00 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24587010 0.98 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24587004 0.88 MEN1 (0.49) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24587564 0.88 MEN1 (0.49) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24587456 0.86 MEN1 (0.50) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL29254327 0.82 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24587858 0.81 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AL3MBTL1CA12
SCHEMBL24586993 0.81 EPHX2 (0.36) ALDH1A1EPHX2GBA2
SCHEMBL25288877 0.80 EPHX2 (0.52) ALDH1A1MEN1KMT2AEPHX2
SCHEMBL24587012 0.79 EPHX2 (0.36) ALDH1A1MEN1KMT2AL3MBTL1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. 2023-11-09 US disclosed
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. 2023-11-09 US disclosed
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. 2023-11-09 US disclosed
EP-4262818-A1 NANOMATERIALS COMPRISING CARBONATES Beam Therapeutics Inc. (US) 2023-10-25 EP disclosed
WO-2022140239-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed
WO-2022140239-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES PHOSPHO1, CA13, SGMS2 ALDH1A1 3544/4885MEN1 882/4885KMT2A 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.