Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | TYK2 | P29597 | 7/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177879 | 0.79 | TYK2 (0.42) | TYK2NR1H2NR1H3HRH1HRH4 | |
| SCHEMBL21354998 | 0.78 | MAP3K12 (0.43) | TYK2NR1H2NR1H3HRH1HRH4 | |
| SCHEMBL17173652 | 0.76 | TYK2 (0.34) | TYK2NR1H2NR1H3KDM4EGPR119 | |
| SCHEMBL17196388 | 0.75 | PTAFR (0.34) | TYK2NR1H2NR1H3KDM4EGPR119 | |
| SCHEMBL24458063 | 0.75 | KDM4E (0.36) | MAT2ADHODHHRH1HRH4HRH3 | |
| SCHEMBL28846981 | 0.73 | LRRK2 (0.39) | LRRK2KDM4E | |
| Hydrochloric Acid SCHEMBL28846926 | 0.72 | LRRK2 (0.38) | LRRK2KDM4E | |
| SCHEMBL24588117 | 0.71 | LRRK2 (0.41) | LRRK2TYK2PIK3CAMTOR | |
| SCHEMBL24588385 | 0.71 | PTGS2 (0.38) | LRRK2DHODHKDM4EPIK3CA | |
| SCHEMBL27102683 | 0.71 | HRH4 (0.33) | MAT2AHRH1HRH4HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |