Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24587301 | 0.72 | KDM4E (0.35) | FPR2KDM4EPDGFRBPDGFRA | |
| SCHEMBL24588293 | 0.72 | PGK1 (0.40) | PDE10APGK1 | |
| SCHEMBL24588281 | 0.72 | PGK1 (0.31) | PGK1 | |
| SCHEMBL22272004 | 0.69 | KDM4E (0.33) | FPR2KDM4EPDGFRBPDGFRA | |
| SCHEMBL17504803 | 0.67 | SMN1; SMN2 (0.36) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL20848120 | 0.67 | KDM4E (0.33) | FPR2KDM4EPDGFRBPDGFRA | |
| SCHEMBL19453382 | 0.66 | KDM4E (0.35) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL20848148 | 0.66 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL32678469 | 0.66 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL32678467 | 0.66 | ALDH1A1 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |