Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582483 | 0.86 | MAPT (0.47) | PAOXMAPTSLC2A1CYP2C19POLB | |
| SCHEMBL26719498 | 0.81 | CYP2C19 (0.43) | PAOXCYP2C19POLBBLMATM | |
| SCHEMBL26564664 | 0.78 | CHRM1 (0.44) | PAOXMAPTSLC2A1ALDH1A1CHRM1 | |
| SCHEMBL16061075 | 0.77 | CPB2 (0.42) | PAOXMAPTALDH1A1CHRM1CHRM2 | |
| SCHEMBL16061073 | 0.77 | CPB2 (0.42) | PAOXMAPTALDH1A1CHRM1CHRM2 | |
| SCHEMBL10582700 | 0.77 | ALDH1A1 (0.54) | PAOXCYP2C19POLBBLMATM | |
| SCHEMBL18032804 | 0.76 | CYP2C19 (0.41) | CYP2C19POLBBLMATMALDH1A1 | |
| SCHEMBL27822244 | 0.75 | CYP2C19 (0.55) | MAPTCYP2C19POLBBLMATM | |
| SCHEMBL7908937 | 0.75 | CYP2C19 (0.55) | CYP2C19POLBBLMATMALDH1A1 | |
| SCHEMBL2736682 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140252-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | BEAM THERAPEUTICS INC. (US) | 2022-06-30 | — | — | WO | disclosed |