SCHEMBL24587789

SCHEMBL24587789

C[Si](C)(C)CCOC(=O)NCCCN

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.52
PAOX Q6QHF9 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25488667 0.93 ACHE (0.50) ACHEPAOX
SCHEMBL6946858 0.89 ACHE (0.46) ACHE
Hydrochloric Acid SCHEMBL6837623 0.87 ACHE (0.44) ACHE
SCHEMBL22134435 0.84 ACHE (0.58) ACHE
SCHEMBL18466200 0.83 ACHE (0.37) ACHEPAOX
SCHEMBL20733124 0.83 ACHE (0.57) ACHEPAOX
SCHEMBL29722729 0.82 ACHE (0.60) ACHE
SCHEMBL3900003 0.81 ACHE (0.66) ACHE
SCHEMBL17660550 0.81 ACHE (0.34) ACHEPAOX
SCHEMBL30250342 0.81 ACHE (0.50) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452930-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES Beam Therapeutics Inc. (US) 2024-10-30 EP disclosed
EP-4262819-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS Beam Therapeutics Inc. (US) 2023-10-25 EP disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
CN-116887841-A Nanomaterials comprising ester-linked acetals 比姆医疗股份有限公司 2023-10-13 CN disclosed
WO-2023121970-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES BEAM THERAPEUTICS INC. (US) 2023-06-29 WO disclosed
WO-2022140252-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed
WO-2022140252-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS LIPA, SGMS1, SGMS2 ACHE 2069/4885PAOX 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.