Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737066 | 1.00 | JAK1 (0.33) | JAK1KDM4EDDB1CRBNALDH1A1 | |
| SCHEMBL30111817 | 0.87 | HCAR1 (0.41) | JAK1USP30GPR119HCAR1FPR2 | |
| SCHEMBL18289981 | 0.87 | HCAR1 (0.41) | JAK1USP30GPR119HCAR1FPR2 | |
| SCHEMBL18818280 | 0.87 | HCAR1 (0.41) | JAK1USP30GPR119HCAR1FPR2 | |
| SCHEMBL18285718 | 0.87 | HCAR1 (0.41) | JAK1USP30GPR119HCAR1FPR2 | |
| SCHEMBL18818279 | 0.87 | HCAR1 (0.41) | JAK1USP30GPR119HCAR1FPR2 | |
| SCHEMBL29737131 | 0.83 | KDM4E (0.37) | JAK1KDM4ESPRCCNT1CDK9 | |
| SCHEMBL24590579 | 0.83 | KDM4E (0.37) | JAK1KDM4ESPRCCNT1CDK9 | |
| SCHEMBL22902683 | 0.82 | JAK1 (0.38) | JAK1ALDH1A1JAK3 | |
| SCHEMBL22902497 | 0.81 | ALDH1A1 (0.34) | ALDH1A1SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140511-A1 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3- DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | GENZYME CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |