Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | PAM | P19021 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40322 | 0.86 | LMNA (0.33) | TSHRLMNA | |
| SCHEMBL1779515 | 0.79 | TSHR (0.44) | TSHRSLC22A6LMNACYP1A2ALDH1A1 | |
| SCHEMBL27710497 | 0.77 | TSHR (0.46) | TSHRSLC22A6LMNACYP1A2ALDH1A1 | |
| SCHEMBL2304455 | 0.76 | LMNA (0.47) | TSHRSLC22A6LMNACYP1A2ALDH1A1 | |
| SCHEMBL1336208 | 0.76 | MGAM (0.40) | — | |
| SCHEMBL2148441 | 0.75 | TSHR (0.52) | TSHRSLC22A6LMNAPAMALDH1A1 | |
| SCHEMBL28959487 | 0.75 | TSHR (0.40) | TSHRSLC22A6LMNACYP1A2ALDH1A1 | |
| SCHEMBL10594433 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL2306638 | 0.75 | LMNA (0.50) | TSHRSLC22A6LMNAALDH1A1MAPK1 | |
| SCHEMBL5969501 | 0.75 | MGAM (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357540-B2 | For immobilization of amines such as an amino-containing analyte, amino acid, DNA, RNA, protein, cell, tissue, organelle, immunoglobin, or fragment; acrylic ester or amide polymers with pendant fluoroalkoxycarbonyl groups; useful in the medical diagnosis of a disease or of a genetic defect | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-01-22 | — | — | US | disclosed |
| EP-1699790-B1 | SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-1700107-B1 | ACOUSTIC SENSORS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-2104689-B1 | POLYMERIC SUBSTRATES WITH FLUOROALKOXYCARBONYL GROUPS FOR AMINE CAPTURE | 3M INNOVATIVE PROPERTIES CO (US) | 2010-05-05 | — | — | EP | disclosed |
| EP-2104689-A1 | POLYMERIC SUBSTRATES WITH FLUOROALKOXYCARBONYL GROUPS FOR AMINE CAPTURE | 3M Innovative Properties Company (US) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008079605-A1 | POLYMERIC SUBSTRATES WITH FLUOROALKOXYCARBONYL GROUPS FOR AMINE CAPTURE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080153175-A1 | POLYMERIC SUBSTRATES WITH FLUOROALKOXYCARBONYL GROUPS FOR AMINE CAPTURE | 3M INNOVATIVE PROPERTIES COMPANY | 2008-06-26 | — | — | US | disclosed |
| US-7342082-B2 | Soluble polymers as amine capture agents and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-03-11 | — | — | US | disclosed |
| WO-2005066092-A9 | ACOUSTIC SENSORS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2006-09-14 | — | — | WO | disclosed |
| EP-1699790-A2 | SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS | 3M Innovative Properties Company (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1700107-A2 | ACOUSTIC SENSORS AND METHODS | 3M Innovative Properties Company (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060135718-A1 | Soluble polymers as amine capture agents and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2006-06-22 | — | — | US | disclosed |
| WO-2005065370-A2 | SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005066092-A2 | ACOUSTIC SENSORS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |