Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285283 | 0.88 | EGLN1 (0.43) | TSHRPAMSLC22A6LMNAALDH1A1 | |
| SCHEMBL17169822 | 0.87 | PAM (0.50) | TSHRPAMLMNAALDH1A1TDP1 | |
| SCHEMBL1515413 | 0.83 | TSHR (0.56) | TSHRPAMSLC22A6LMNANFKB1 | |
| SCHEMBL23049031 | 0.82 | TSHR (0.50) | TSHRPAMSLC22A6LMNANFKB1 | |
| SCHEMBL9133055 | 0.82 | PAM (0.41) | TSHRPAMLMNAALDH1A1TDP1 | |
| SCHEMBL3504158 | 0.82 | PAM (0.55) | TSHRPAMLMNAALDH1A1TDP1 | |
| SCHEMBL585970 | 0.81 | PAM (0.63) | TSHRPAMSLC22A6LMNANFKB1 | |
| SCHEMBL3503610 | 0.80 | PAM (0.63) | TSHRPAMLMNAALDH1A1MEN1 | |
| SCHEMBL3503950 | 0.78 | PAM (0.67) | TSHRPAMLMNAALDH1A1MEN1 | |
| SCHEMBL3504155 | 0.78 | PAM (0.67) | TSHRPAMLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8591923-B2 | Cosmetic compositon comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL (FR) | 2013-11-26 | — | — | US | claimed |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL S.A. (FR) | 2007-08-16 | — | — | US | claimed |
| EP-1797868-A1 | Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | claimed |
| EP-2729118-A2 | COSMETIC TREATMENT PROCESSES AND KIT | L'OREAL (FR) | 2014-05-14 | — | — | EP | disclosed |
| US-8591923-B2 | Cosmetic compositon comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL (FR) | 2013-11-26 | — | — | US | disclosed |
| WO-2013004982-A2 | COSMETIC TREATMENT PROCESSES AND KIT | L'OREAL (FR) | 2013-01-10 | — | — | WO | disclosed |
| WO-2011083243-A1 | COSMETIC TREATMENT METHODS AND KIT | L'OREAL (FR) | 2011-07-14 | — | — | WO | disclosed |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL S.A. (FR) | 2007-08-16 | — | — | US | disclosed |
| EP-1797868-A1 | Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | KRT18, TST, CTH | TSHR 2129/4885PAM 791/4885SLC22A6 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.