SCHEMBL2459079

SCHEMBL2459079

C=COCCCOC(=O)C=C

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.68
ALDH1A1 P00352 4/20 0.68
CYP3A4 P08684 2/20 0.68
HPGD P15428 1/20 0.61
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
HSD17B10 Q99714 1/20 0.56
THRB P10828 3/20 0.42
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2456633 0.96 TSHR (0.75) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18823427 0.94 TSHR (0.79) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18822946 0.94 TSHR (0.79) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2456155 0.94 TSHR (0.79) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18823424 0.94 TSHR (0.79) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.89 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20459819 0.88 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL278577 0.86 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28470987 0.86 TSHR (0.81) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27845138 0.85 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101497630-A Phosphoric acrylic ester monomer, hyperbranched polymer flame retardant and preparation thereof ANHUI HENGYUAN CHEMICAL CO LTD (CN) 2009-08-05 CN claimed
US-5100660-A Cationic Polymers ALLIED COLLOIDS LIMITED (GB) 1992-03-31 US claimed
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
CN-102439523-B Method and materials for double patterning DOW CORNING 2015-01-07 CN disclosed
US-8158748-B2 Hetero-functional compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2012-04-17 US disclosed
US-8158748-B2 Hetero-functional compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2012-04-17 US disclosed
CN-101497630-B Phosphoric acrylic ester monomer, hyperbranched polymer flame retardant and preparation thereof ANHUI HENGYUAN CHEMICAL CO LTD 2011-10-26 CN disclosed
US-8017718-B2 radiation curable conjugate addition reaction product of nucleophiles with vinyloxyalkyl acrylates, having high molecular weights and low volatility, useful as coatings or adhesives PPG INDUSTRIES OHIO, INC. (US) 2011-09-13 US disclosed
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-02-18 US disclosed
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-02-18 US disclosed
CN-101497630-A Phosphoric acrylic ester monomer, hyperbranched polymer flame retardant and preparation thereof ANHUI HENGYUAN CHEMICAL CO LTD (CN) 2009-08-05 CN disclosed
US-20080227927-A1 VINYL ETHERS AND COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. (US) 2008-09-18 US disclosed
US-7411033-B2 Vinyl ethers and compositions containing them PPG INDUSTRIES OHIO, INC. (US) 2008-08-12 US disclosed
US-20070293652-A1 VINYL ETHERS AND COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus KAT8, TAS2R8, NLRP3 TSHR 3114/4885ALDH1A1 207/4885CYP3A4 1730/4885
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF C9, C3AR1, C1S TSHR 4373/4885ALDH1A1 1455/4885CYP3A4 2077/4885
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method JAK1, EED, PI4KA TSHR 4124/4885ALDH1A1 1184/4885CYP3A4 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.