Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20876287 | 0.79 | NEU3 (0.36) | USP2 | |
| SCHEMBL19456379 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL20876289 | 0.74 | KMT2A (0.42) | — | |
| SCHEMBL20887369 | 0.73 | BRD4 (0.45) | — | |
| SCHEMBL29955832 | 0.63 | PTGS2 (0.52) | PTPN1 | |
| SCHEMBL16348552 | 0.63 | HDAC8 (0.47) | — | |
| SCHEMBL20887077 | 0.62 | PARP1 (0.42) | — | |
| SCHEMBL3934286 | 0.61 | MMP13 (0.40) | — | |
| SCHEMBL1852687 | 0.61 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL2511971 | 0.61 | PTPN1 (0.45) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692026-B1 | BENZOFURAN DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS. | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2022-07-06 | — | — | EP | disclosed |