SCHEMBL24594128

SCHEMBL24594128

CCc1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.64
▸ DNASE1L3 Q13609 1/20 0.60
▸ PRMT1 Q99873 1/20 0.60
▸ MEN1 O00255 2/20 0.59
▸ POLB P06746 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ ALPL P05186 1/20 0.59
▸ ALPI P09923 1/20 0.59
▸ ALPG P10696 1/20 0.59
▸ ATM Q13315 1/20 0.57
▸ PLEC Q15149 1/20 0.57
▸ ESR1 P03372 1/20 0.53
▸ CA9 Q16790 11/20 0.52
▸ CA1 P00915 9/20 0.52
▸ CA2 P00918 9/20 0.52
▸ CA12 O43570 4/20 0.52
▸ CA14 Q9ULX7 3/20 0.52
▸ CA7 P43166 3/20 0.51
▸ ALB P02768 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060092 0.93 USP2 (0.72) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL18754815 0.90 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL22107769 0.90 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL18211419 0.89 USP2 (0.61) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL22650188 0.89 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL20256560 0.87 USP2 (0.59) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL23158776 0.87 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL12045940 0.86 USP2 (0.68) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL14642481 0.86 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL23762550 0.86 USP2 (0.57) USP2L3MBTL1DNASE1L3PRMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283499-B1 DUAL QUENCHER PROBES BIOSEARCH TECH INC (US) 2022-07-06 — — EP disclosed
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