Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PLEC | Q15149 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 14/20 | 0.57 |
| ▸ | CA1 | P00915 | 12/20 | 0.57 |
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24594128 | 0.93 | USP2 (0.64) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL20056705 | 0.90 | USP2 (0.69) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL14619875 | 0.89 | USP2 (0.72) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL13369020 | 0.89 | USP2 (0.75) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL18383481 | 0.89 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL29668458 | 0.89 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL23318855 | 0.87 | USP2 (0.66) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10098714 | 0.86 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL14563221 | 0.85 | USP2 (0.69) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL12637647 | 0.85 | USP2 (0.72) | USP2L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128591-A1 | IONIC POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | SONY CORPORATION (JP) | 2021-05-06 | — | — | US | disclosed |
| US-10688198-B2 | Salicylic acid-based polymeric CEST contrast agents targeting prostate-specific membrane antigen and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-23 | — | — | US | disclosed |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2019-10-08 | — | — | US | disclosed |
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20070065898-A1 | Fluorescence polarization assays for binding of caspase inhibitors and probes therefor | WYETH (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688198-B2 | Salicylic acid-based polymeric CEST contrast agents targeting prostate-specific membrane antigen and uses thereof | KLK3, PSAT1, SPAG5 | USP2 785/4885L3MBTL1 4066/4885MEN1 2155/4885 |
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | FOLH1, KLK3, PSMA2 | USP2 3252/4885L3MBTL1 2898/4885MEN1 190/4885 |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | HDAC1, HDAC3, HDAC11 | USP2 2116/4885L3MBTL1 1410/4885MEN1 3684/4885 |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | DNPEP, ENPEP, PEPD | USP2 841/4885L3MBTL1 3802/4885MEN1 4381/4885 |
| US-20070065898-A1 | Fluorescence polarization assays for binding of caspase inhibitors and probes therefor | APAF1, CASP1, CASP14 | USP2 3883/4885L3MBTL1 1433/4885MEN1 2203/4885 |
| US-20210128591-A1 | IONIC POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | TLN1, MRPL21, TLL1 | USP2 4039/4885L3MBTL1 7/4885MEN1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.