SCHEMBL20256560

SCHEMBL20256560

CC(C)(C)C(=O)Cc1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ DNASE1L3 Q13609 1/20 0.56
▸ PRMT1 Q99873 1/20 0.56
▸ MEN1 O00255 2/20 0.55
▸ POLB P06746 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ ALPL P05186 1/20 0.55
▸ ALPI P09923 1/20 0.55
▸ ALPG P10696 1/20 0.55
▸ ATM Q13315 1/20 0.53
▸ PLEC Q15149 1/20 0.53
▸ CA9 Q16790 11/20 0.49
▸ CA1 P00915 9/20 0.49
▸ CA2 P00918 9/20 0.49
▸ CA12 O43570 4/20 0.49
▸ CA14 Q9ULX7 3/20 0.49
▸ CA7 P43166 3/20 0.48
▸ ESR1 P03372 1/20 0.48
▸ ALB P02768 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23318855 0.93 USP2 (0.66) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL23158776 0.92 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL18754815 0.89 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL22107769 0.89 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL22650188 0.89 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL24594128 0.87 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL23762550 0.85 USP2 (0.57) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL18211419 0.85 USP2 (0.61) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL13401323 0.83 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL19370241 0.83 USP2 (0.64) USP2L3MBTL1DNASE1L3PRMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-11377563-B2 Ionic polymers comprising fluorescent or colored reporter groups SONY CORPORATION (JP) 2022-07-05 — — US disclosed
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-06-02 — — US disclosed
US-11312736-B1 Programmable polymeric drugs SONY CORPORATION (JP) 2022-04-26 — — US disclosed
US-10989715-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION (JP) 2021-04-27 — — US disclosed
US-10866244-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2020-12-15 — — US disclosed
US-20200360526-A1 PHOSPHOALKYL POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS Sony Group Corporation (JP) 2020-11-19 — — US disclosed
US-20200353094-A1 PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS Sony Group Corporation (JP) 2020-11-12 — — US disclosed
US-20200284798-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2020-09-10 — — US disclosed
US-20200222554-A1 PROGRAMMABLE DENDRITIC DRUGS Sony Group Corporation (JP) 2020-07-16 — — US disclosed
US-20190300716-A1 IONIC POLYMERS COMPRISING FLUORESCENT OR COLORED REPORTER GROUPS SONY CORPORATION (JP) 2019-10-03 — — US disclosed
US-20190136065-A1 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF Sony Group Corporation (JP) 2019-05-09 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200284798-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-11312736-B1 Programmable polymeric drugs NCL, PBRM1, LPXN USP2 2142/4885L3MBTL1 81/4885DNASE1L3 446/4885
US-10866244-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-20200353094-A1 PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS PARP1, PARP11, PHOSPHO1 USP2 2969/4885L3MBTL1 68/4885DNASE1L3 280/4885
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, PBRM1, CHRM2 USP2 1989/4885L3MBTL1 15/4885DNASE1L3 830/4885
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-10989715-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885DNASE1L3 1738/4885
US-20200360526-A1 PHOSPHOALKYL POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS PHOSPHO1, PGM2, PHYKPL USP2 3659/4885L3MBTL1 28/4885DNASE1L3 845/4885
US-20200222554-A1 PROGRAMMABLE DENDRITIC DRUGS CHRM1, TLL1, TEX264 USP2 3448/4885L3MBTL1 19/4885DNASE1L3 417/4885
US-11377563-B2 Ionic polymers comprising fluorescent or colored reporter groups IK, PUF60, ALG1 USP2 3923/4885L3MBTL1 1286/4885DNASE1L3 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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