⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526298 | 1.00 | — | — | |
| SCHEMBL8585951 | 0.74 | MAPT (0.44) | — | |
| SCHEMBL6279062 | 0.73 | — | — | |
| SCHEMBL2064738 | 0.63 | TSHR (0.42) | — | |
| SCHEMBL8563469 | 0.62 | ITGB3 (0.35) | — | |
| SCHEMBL7875920 | 0.62 | EGLN1 (0.35) | — | |
| SCHEMBL4224698 | 0.62 | ITGB3 (0.35) | — | |
| SCHEMBL23829881 | 0.59 | — | — | |
| SCHEMBL9102893 | 0.59 | — | — | |
| SCHEMBL10350217 | 0.59 | IDUA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159692-A1 | IMPROVED METHODS FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS | THE NEW YORK STEM CELL FOUNDATION (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011113036-A2 | COMPOSITIONS AND METHODS FOR EXPANDING BFU-E CELLS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2011-09-15 | — | — | WO | disclosed |
| EP-1506409-A1 | ASSAYS FOR MODULATORS OF ASPARAGINYL HYDROXYLASE | ISIS INNOVATION LIMITED (GB) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003100438-A1 | ASSAYS FOR MODULATORS OF ASPARAGINYL HYDROXYLASE | ISIS INNOVATION LIMITED (GB) | 2003-12-04 | — | — | WO | disclosed |