Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078244 | 0.85 | KMT2A (0.46) | HTTTSHRTP53KMT2AMEN1 | |
| SCHEMBL18078203 | 0.79 | NPSR1 (0.45) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL13489680 | 0.76 | CTSK (0.43) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL13489686 | 0.75 | KMT2A (0.44) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL19871022 | 0.75 | NPSR1 (0.43) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL24595330 | 0.72 | KMT2A (0.44) | HTTTSHRTP53KMT2AMEN1 | |
| SCHEMBL15764475 | 0.71 | TSHR (0.40) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL6177428 | 0.70 | NPSR1 (0.51) | HTTTSHRTP53NPSR1KMT2A | |
| SCHEMBL13319543 | 0.69 | ALDH1A1 (0.48) | TSHRTP53KMT2AMEN1HSD17B10 | |
| SCHEMBL6295326 | 0.69 | AAK1 (0.44) | HTTTSHRTP53NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023645-A1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | Aurigene Discovery Technologies Limited (IN) | 2022-07-06 | — | — | EP | disclosed |