Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535504 | 0.91 | TP53 (0.48) | NPC1RAB9APTPN7MEN1KMT2A | |
| SCHEMBL25901149 | 0.91 | THRB (0.51) | THRBMEN1KMT2AACHEMAOB | |
| SCHEMBL18583378 | 0.90 | THRB (0.42) | THRBNPC1RAB9APTPN7MEN1 | |
| SCHEMBL21116035 | 0.88 | ACHE (0.42) | THRBNPC1RAB9APTPN7MEN1 | |
| SCHEMBL18583373 | 0.87 | THRB (0.41) | THRBNPC1RAB9APTPN7MEN1 | |
| SCHEMBL18535617 | 0.87 | NPC1 (0.41) | NPC1RAB9APTPN7MEN1KMT2A | |
| SCHEMBL21116026 | 0.87 | THRB (0.45) | THRBNPC1RAB9APTPN7MEN1 | |
| SCHEMBL18583697 | 0.87 | THRB (0.40) | THRBNPC1RAB9APTPN7MEN1 | |
| SCHEMBL18535602 | 0.86 | ACHE (0.45) | NPC1RAB9APTPN7MEN1KMT2A | |
| SCHEMBL18583698 | 0.85 | STS (0.48) | NPC1RAB9APTPN7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327779-A2 | SYSTEM AND METHOD | AMO Ireland (IE) | 2024-02-28 | — | — | EP | disclosed |
| EP-3958788-B1 | SYSTEM AND METHOD | AMO Ireland (IE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |