Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535505 | 0.86 | NPC1 (0.42) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL24590534 | 0.84 | MAOB (0.42) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL21524280 | 0.83 | KDM4E (0.35) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18535454 | 0.78 | MIF (0.57) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL24595646 | 0.74 | RXFP1 (0.42) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL21116041 | 0.73 | THRB (0.36) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL25848189 | 0.71 | THRB (0.41) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL25848158 | 0.71 | THRB (0.41) | RXFP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL23893565 | 0.69 | THRB (0.39) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL24595670 | 0.69 | KLK7 (0.40) | RXFP1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |