Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27105756 | 0.86 | RXFP1 (0.41) | RXFP1KLK7NPC1RAB9AKMT2A | |
| SCHEMBL21116162 | 0.80 | KDM4E (0.38) | RXFP1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL18535528 | 0.78 | KDM4E (0.48) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL23713569 | 0.74 | STS (0.46) | RXFP1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL23893515 | 0.74 | ALDH1A1 (0.40) | KLK7NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL24595672 | 0.74 | RXFP1 (0.38) | RXFP1KLK7NPC1RAB9AKMT2A | |
| SCHEMBL21116509 | 0.72 | RXFP1 (0.38) | RXFP1KLK7NPC1RAB9AKMT2A | |
| SCHEMBL21116038 | 0.71 | NPC1 (0.39) | RXFP1KLK7NPC1RAB9AKMT2A | |
| SCHEMBL26854645 | 0.70 | KLK7 (0.42) | RXFP1KLK7NPC1RAB9AKMT2A | |
| SCHEMBL18535532 | 0.70 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958788-B1 | SYSTEM AND METHOD | AMO Ireland (IE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |