SCHEMBL24599191

SCHEMBL24599191

C=C(C)C(=O)OCCNC(=O)N(CCN(C(=O)NCCOC(=O)C(=C)C)C(C)(C)C)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24599190 0.92 THRB (0.38) THRBTSHRPOLBAPEX1HTT
SCHEMBL10093553 0.92 THRB (0.36) THRBTSHRALDH1A1MEN1CYP1A2
SCHEMBL17483782 0.90 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL24599169 0.87 TSHR (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11317622 0.85 TSHR (0.48) THRBTSHR
SCHEMBL17758703 0.84 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17483780 0.83 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23153173 0.81 ACHE (0.43) TSHR
SCHEMBL17756350 0.80 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9067254 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084192-A1 REPROCESSABLE ADDITION-TYPE POLYMER NETWORKS BASED ON DYNAMIC HINDERED UREA BONDS NORTHWESTERN UNIVERSITY 2025-03-13 US claimed
WO-2023158921-A2 REPROCESSABLE ADDITION-TYPE POLYMER NETWORKS BASED ON DYNAMIC HINDERED UREA BONDS NORTHWESTERN UNIVERSITY (US) 2023-08-24 WO claimed
US-20250084192-A1 REPROCESSABLE ADDITION-TYPE POLYMER NETWORKS BASED ON DYNAMIC HINDERED UREA BONDS NORTHWESTERN UNIVERSITY 2025-03-13 US disclosed
WO-2023158921-A2 REPROCESSABLE ADDITION-TYPE POLYMER NETWORKS BASED ON DYNAMIC HINDERED UREA BONDS NORTHWESTERN UNIVERSITY (US) 2023-08-24 WO disclosed
WO-2022144728-A1 ADHESIVE WITH THERMALLY REVERSIBLE, COVALENT CROSSLINKS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-07-07 WO disclosed