Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599204 | 0.88 | KDM4A (0.42) | ALDH1A1KMT2AKDM4ETNKSTSHR | |
| SCHEMBL24599203 | 0.80 | KDR (0.41) | MAPK14TNKSMAPTPARP1ADORA3 | |
| SCHEMBL23361516 | 0.76 | POLB (0.43) | MAPK14NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL15527637 | 0.75 | TNKS (0.47) | MAPK14NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL23361611 | 0.75 | TNKS (0.38) | MAPK14ALDH1A1KMT2AKDM4ETNKS | |
| SCHEMBL16611551 | 0.74 | ALKBH5 (0.44) | KMT2ASMN1; SMN2TNKSMAPTERCC1 | |
| SCHEMBL16731004 | 0.74 | S1PR1 (0.37) | KDM4ESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL23140215 | 0.72 | PIK3CA (0.42) | — | |
| SCHEMBL15604819 | 0.71 | TNKS (0.48) | MAPK14NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16611005 | 0.71 | S1PR1 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228500-A1 | THERAPEUTIC CONJUGATES | TOTUS MEDICINES INC. | 2024-07-11 | — | — | US | disclosed |
| US-12029791-B2 | Therapeutic conjugates | TOTUS MEDICINES INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20220387603-A1 | THERAPEUTIC CONJUGATES | TOTUS MEDICINES INC. | 2022-12-08 | — | — | US | disclosed |
| US-20220211855-A1 | THERAPEUTIC CONJUGATES | TOTUS MEDICINES INC. | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029791-B2 | Therapeutic conjugates | CD47, CD44, EPCAM | MAPK14 4714/4885NPC1 686/4885RAB9A 1120/4885 |
| US-20240228500-A1 | THERAPEUTIC CONJUGATES | CD47, CD44, EPCAM | MAPK14 4714/4885NPC1 686/4885RAB9A 1120/4885 |
| US-20220387603-A1 | THERAPEUTIC CONJUGATES | CD47, CD44, EPCAM | MAPK14 4714/4885NPC1 686/4885RAB9A 1120/4885 |
| US-20220211855-A1 | THERAPEUTIC CONJUGATES | CD47, CD44, EPCAM | MAPK14 4714/4885NPC1 686/4885RAB9A 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.