Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.37 |
| ▸ | CHUK | O15111 | 9/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 9/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600504 | 0.83 | PDE3B (0.36) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| SCHEMBL26877422 | 0.83 | ADRB2 (0.41) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| SCHEMBL26679987 | 0.81 | ENPP1 (0.38) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| SCHEMBL24600503 | 0.80 | PRKCI (0.43) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| Hydrochloric Acid SCHEMBL29691541 | 0.79 | PRKCI (0.42) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| Hydrochloric Acid SCHEMBL26679823 | 0.79 | PRKCI (0.42) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| SCHEMBL24600558 | 0.79 | ENPP1 (0.56) | ENPP1CHUKIKBKBENPP3ROCK1 | |
| SCHEMBL29691620 | 0.79 | ENPP1 (0.56) | ENPP1CHUKIKBKBENPP3ROCK1 | |
| SCHEMBL29248802 | 0.79 | ENPP1 (0.44) | ENPP1CHUKMAPK8INSRCAMKK2 | |
| SCHEMBL26679935 | 0.79 | IKBKB (0.46) | ENPP1CHUKMAPK8INSRCAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |