Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 4/20 | 0.44 |
| ▸ | CHUK | O15111 | 9/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 9/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CIT | O14578 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546582 | 0.85 | ENPP1 (0.39) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL26877422 | 0.82 | ADRB2 (0.41) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL24600503 | 0.82 | PRKCI (0.43) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| Hydrochloric Acid SCHEMBL29691541 | 0.81 | PRKCI (0.42) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| Hydrochloric Acid SCHEMBL26679823 | 0.81 | PRKCI (0.42) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL29691620 | 0.81 | ENPP1 (0.56) | ENPP1CHUKENPP3IKBKBNEK1 | |
| SCHEMBL24600558 | 0.81 | ENPP1 (0.56) | ENPP1CHUKENPP3IKBKBNEK1 | |
| SCHEMBL24600596 | 0.80 | ENPP1 (0.57) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL26679987 | 0.80 | ENPP1 (0.38) | ENPP1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL24600509 | 0.79 | ENPP1 (0.37) | ENPP1CHUKINSRMAPK8CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |