SCHEMBL24600583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24601338	0.85	KCNH2 (0.42)	KCNH2CYP1A2CYP2D6CYP3A4CACNA1F
	SCHEMBL26239278	0.80	KCNH2 (0.39)	KCNH2ALDH1A1KDM4ECYP1A2CYP2D6
	SCHEMBL26239253	0.80	KCNH2 (0.61)	KCNH2ALDH1A1HTTBLMMAPT
	SCHEMBL26240045	0.79	KCNH2 (0.64)	KCNH2ALDH1A1HTTSMN1; SMN2CYP1A2
	SCHEMBL5102530	0.79	CYP2D6 (0.59)	KCNH2ALDH1A1HTTKDM4ESMN1; SMN2
	SCHEMBL10726453	0.79	LMNA (0.50)	KCNH2ALDH1A1HTTKDM4ECYP3A4
	SCHEMBL28092143	0.77	MAPT (0.55)	KCNH2ALDH1A1HTTKDM4ESMN1; SMN2
	SCHEMBL26640241	0.77	GAA (0.51)	ALDH1A1HTTKDM4ESMN1; SMN2CYP1A2
	SCHEMBL26239252	0.77	KCNH2 (0.59)	KCNH2ALDH1A1HTTSMN1; SMN2CYP1A2
	SCHEMBL12121313	0.76	HTR2A (0.52)	ALDH1A1HTTKDM4ESMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.