Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601006 | 0.95 | ADORA3 (0.48) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601226 | 0.92 | ADORA3 (0.44) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601236 | 0.92 | ADORA3 (0.41) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601231 | 0.91 | NT5E (0.42) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601108 | 0.91 | ADORA3 (0.41) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL24601240 | 0.90 | NT5E (0.42) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24601261 | 0.90 | ADORA3 (0.39) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL24601238 | 0.89 | NT5E (0.42) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL30850581 | 0.88 | ADORA3 (0.51) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL26628564 | 0.88 | ADORA3 (0.51) | NT5EADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |