SCHEMBL24601424

SCHEMBL24601424

CC(C)(C)c1ccc2c(c1)c1c3c4ccc(-n5c6ccccc6c6ccccc65)cc4n4c5ccc(C(C)(C)C)cc5c(c5c6ccc(-n7c8ccccc8c8ccccc87)cc6n2c15)c34

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KIF11 P52732 3/20 0.35
PPARG P37231 4/20 0.34
PPARA Q07869 2/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33
HTR1D P28221 1/20 0.33
LMNA P02545 1/20 0.33
KCNH2 Q12809 1/20 0.31
DNMT1 P26358 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601408 0.94 KIF11 (0.38) PGRRORARORCRORBKDM4E
SCHEMBL24601330 0.87 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL22178625 0.87 KIF11 (0.44) PGRRORARORCRORBKDM4E
SCHEMBL22178604 0.85 KDM4E (0.47) KDM4EATML3MBTL1
SCHEMBL24601603 0.85 ALDH1A1 (0.31) KDM4EATML3MBTL1
SCHEMBL23331192 0.84 KDM4E (0.47) PGRRORARORCRORBKDM4E
SCHEMBL22178867 0.84 KIF11 (0.44) PGRRORARORCRORBKDM4E
SCHEMBL24601325 0.84 KDM4E (0.48) KDM4EATML3MBTL1KIF11
SCHEMBL24601610 0.83 KDM4E (0.33) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL22178730 0.82 KDM4E (0.47) KDM4EATML3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 PGR 2243/4885RORA 4465/4885RORC 3561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.