SCHEMBL24601614

SCHEMBL24601614

CC(C)(C)c1cc(-c2cccc3c2c2c4c5ccccc5n5c6cccc(-c7cc(C(C)(C)C)cc(C(C)(C)C)c7)c6c(c6c7ccccc7n3c62)c45)cc(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601416 1.00 RXRA (0.32) RXRARXRBRORC
SCHEMBL24601421 0.89 RXRA (0.32) RXRARXRBRORC
SCHEMBL24601608 0.88 RXRB (0.35) RXRARXRB
SCHEMBL24601602 0.88 NR1H4 (0.36)
SCHEMBL24601541 0.88 NR1H4 (0.36)
SCHEMBL24601470 0.88 RXRA (0.33) RXRARXRB
SCHEMBL24601495 0.86 TSPO (0.30) RXRARXRB
SCHEMBL24601507 0.85 TSPO (0.33) RXRARXRB
SCHEMBL24601523 0.85
SCHEMBL24601613 0.84 DNMT1 (0.34) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 RXRA 4654/4885RXRB 4748/4885RORC 3561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.