SCHEMBL24601651

SCHEMBL24601651

COc1cccc2c3c4c5cccc(-c6cc(C(C)(C)C)cc(C(C)(C)C)c6)c5n5c6c(OC)cccc6c(c6c7cccc(-c8cc(C(C)(C)C)cc(C(C)(C)C)c8)c7n(c12)c36)c45

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.35
CYP19A1 P11511 1/20 0.35
NQO2 P16083 1/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
PABPC1 P11940 1/20 0.35
XBP1 P17861 1/20 0.35
NFKB1 P19838 1/20 0.35
HTT P42858 1/20 0.35
SMARCA2 P51531 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
PTPN5 P54829 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
STK10 O94804 1/20 0.32
SLK Q9H2G2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601765 0.90 RXRA (0.31)
SCHEMBL24601762 0.88 PRMT1 (0.33) PRMT1CYP19A1NQO2KMT2AALDH1A1
SCHEMBL24601650 0.83 RXRA (0.33) PTPN5
SCHEMBL24601766 0.82 RXRA (0.32)
SCHEMBL24601435 0.81
SCHEMBL24601654 0.81 ALDH1A1 (0.35) KMT2AALDH1A1MAPTKDM4EPABPC1
SCHEMBL24601470 0.80 RXRA (0.33) ALDH1A1NFKB1NFKB2RELARAB9A
SCHEMBL24601763 0.80 DHODH (0.33)
SCHEMBL24601769 0.80 PTPN5 (0.33) PTPN5
SCHEMBL24601421 0.79 RXRA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 PRMT1 977/4885CYP19A1 4125/4885NQO2 374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.