Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306835 | 1.00 | TSHR (0.33) | TSHRTP53TDP1 | |
| SCHEMBL2460230 | 1.00 | TSHR (0.33) | TSHRTP53TDP1 | |
| SCHEMBL2463608 | 0.76 | PPARD (0.34) | TSHRTP53TDP1 | |
| SCHEMBL2463607 | 0.76 | PPARD (0.34) | TSHRTP53TDP1 | |
| SCHEMBL14837804 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL16510238 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL14845906 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL15671914 | 0.74 | PPARD (0.32) | TSHR | |
| SCHEMBL11341588 | 0.73 | TSHR (0.43) | TSHRTP53TDP1 | |
| SCHEMBL14328090 | 0.73 | TSHR (0.43) | TSHRTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017596-B2 | Phosphonates useful as modulators of T-γ-9-δ-2 activity | INNATE PHARMA, S.A. (FR) | 2011-09-13 | — | — | US | disclosed |
| US-20100204184-A1 | Phosphonates useful as modulators of T-gamma-9-delta-2 activity | LABORATOIRES MAYOLY SPINDLER (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20060241087-A1 | Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity | MONTERO JEAN-LOUIS | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204184-A1 | Phosphonates useful as modulators of T-gamma-9-delta-2 activity | CD4, PRKCD, PRKCZ | TSHR 1416/4885TP53 1438/4885TDP1 2298/4885 |
| US-20060241087-A1 | Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity | CD4, GNG2, PLCG2 | TSHR 2353/4885TP53 2022/4885TDP1 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.