SCHEMBL2460434

SCHEMBL2460434

CC12CCC(C1)CC2(N=C=O)N=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194754 0.90
SCHEMBL9580448 0.66 ALDH1A1 (0.35)
SCHEMBL3215239 0.65
SCHEMBL27992589 0.65
SCHEMBL1615799 0.65
SCHEMBL7785949 0.64 HSD11B1 (0.33)
SCHEMBL727186 0.64 PLA2G1B (0.34)
SCHEMBL28256196 0.64 PLA2G1B (0.34)
SCHEMBL20703058 0.63
SCHEMBL3207936 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378139-B2 Continuous oligomerization of isocyanates CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-02-19 US claimed
US-20110218314-A1 CONTINUOUS OLIGOMERIZATION OF ISOCYANATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(C.N.R (FR) 2011-09-08 US claimed
EP-1917283-A1 PROCESS AND COMPOSITION FOR THE PREPARATION OF TRANSPARENT POLYURETHANES AND POLYURETHANES OBTAINED THEREFROM Resal S.R.L. (IT) 2008-05-07 EP disclosed
WO-2007015273-A1 PROCESS AND COMPOSITION FOR THE PREPARATION OF TRANSPARENT POLYURETHANES AND POLYURETHANES OBTAINED THEREFROM RESAL S.R.L. (IT) 2007-02-08 WO disclosed
EP-1382626-A1 Modified isocyanates Rhodia Chimie (FR) 2004-01-21 EP disclosed
EP-1007579-B1 METHOD FOR MASKING POLYISOCYANATES IN EMULSION RHODIA CHIMIE SA (FR) 2003-06-04 EP disclosed
WO-2002012366-A1 POLYISOCYANATE COMPOSITION RHODIA CHIMIE (FR) 2002-02-14 WO disclosed
EP-1129120-A1 MODIFIED ISOCYANATES RHODIA CHIMIE (FR) 2001-09-05 EP disclosed
EP-1007579-A1 METHOD FOR MASKING POLYISOCYANATES IN EMULSION RHODIA CHIMIE (FR) 2000-06-14 EP disclosed
WO-2000020477-A1 MODIFIED ISOCYANATES RHODIA CHIMIE (FR) 2000-04-13 WO disclosed
WO-1999010402-A1 METHOD FOR MASKING POLYISOCYANATES IN EMULSION RHODIA CHIMIE (FR) 1999-03-04 WO disclosed