Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 4/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606015 | 0.92 | EGFR (0.44) | EGFRALKIGF1RINSRMAP4K1 | |
| SCHEMBL29710725 | 0.90 | EGFR (0.58) | EGFRALKIGF1RINSRMAP4K1 | |
| SCHEMBL26630856 | 0.90 | EGFR (0.58) | EGFRALKIGF1RINSRMAP4K1 | |
| SCHEMBL24605983 | 0.89 | ALK (0.63) | ALKIGF1RINSRPTK2 | |
| SCHEMBL22804399 | 0.87 | EGFR (0.63) | EGFRALKIGF1RINSR | |
| SCHEMBL24605929 | 0.86 | INSR (0.50) | EGFRALKIGF1RINSRPTK2 | |
| SCHEMBL24605951 | 0.83 | PTK2 (0.52) | EGFRALKPTK2 | |
| SCHEMBL24606022 | 0.82 | EGFR (0.50) | EGFRALKIGF1RINSRMAP4K1 | |
| SCHEMBL29710836 | 0.82 | EGFR (0.49) | EGFRALKIGF1RINSRMAP4K1 | |
| SCHEMBL30782763 | 0.82 | ALK (0.45) | EGFRALKIGF1RINSRMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146027-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-07 | — | — | WO | disclosed |