Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939268 | 0.87 | NCEH1 (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL593520 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30356865 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13880496 | 0.83 | CDC25B (0.63) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL71131 | 0.82 | NCEH1 (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8782101 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29404644 | 0.82 | NCEH1 (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL244541 | 0.82 | LDHA (0.62) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL161927 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16384835 | 0.81 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302722-A1 | COPOLYETHER ESTER ELASTOMER | INVISTA NORTH AMERICA S.A.R.L (US) | 2012-11-29 | — | — | US | claimed |
| EP-2510039-A1 | COPOLYETHER ESTER ELASTOMER | Invista Technologies S.à.r.l. (CH) | 2012-10-17 | — | — | EP | claimed |
| WO-2011071558-A1 | COPOLYETHER ESTER ELASTOMER | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2011-06-16 | — | — | WO | claimed |
| CN-118580225-A | PRMT5-MTA synergistic inhibitor and application thereof | 甘李药业股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-111936576-B | Thermoplastic resin composition and molded product made therefrom | 乐天化学株式会社 | 2023-10-17 | — | — | CN | disclosed |
| CN-111936576-A | Thermoplastic resin composition and molded product made therefrom | 乐天化学株式会社 | 2020-11-13 | — | — | CN | disclosed |
| WO-2018005249-A1 | BENZOISOQUINOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2018-01-04 | — | — | WO | disclosed |
| WO-2017160670-A1 | M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017160670-A1 | M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-09-21 | — | — | WO | disclosed |
| EP-2709451-B1 | N-LINKED LACTAM M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2015-12-30 | — | — | EP | disclosed |
| EP-2709451-B1 | N-LINKED LACTAM M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2010110554-A2 | ORGANIC ELECTROLUMINESCENT DEVICE USING ORGANIC ELECTROLUMINESCENT COMPOUNDS | DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) | 2010-09-30 | — | — | WO | disclosed |
| US-6833428-B1 | Polyetherester elastomer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-12-21 | — | — | US | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4757130-A | Condensation polymers with pendant side chains exhibiting nonlinear optical response | HOECHST CELANESE CORPORATON (US) | 1988-07-12 | — | — | US | disclosed |
| US-4540705-A | Antidepressant imidazolines and related compounds | STERLING DRUG INC. (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0125410-A2 | Imidazolines and related compounds and preparation thereof | STERLING DRUG INC. (US) | 1984-11-21 | — | — | EP | disclosed |