SCHEMBL244541

SCHEMBL244541

COC(=O)c1ccc2ccccc2c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.62
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
MAPT P10636 3/20 0.60
KDM4A O75164 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
KDM4C Q9H3R0 1/20 0.54
KDM4E B2RXH2 3/20 0.53
ATM Q13315 1/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 1/20 0.53
CYP1B1 Q16678 2/20 0.52
ABCG2 Q9UNQ0 2/20 0.52
CYP1A1 P04798 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7162822 0.88 LDHA (0.54) LDHAKMT2AMEN1MAPTKDM4A
SCHEMBL30356865 0.84 MAPT (0.61) LDHAKMT2AMEN1MAPTKDM4E
SCHEMBL593520 0.84 MAPT (0.61) LDHAKMT2AMEN1MAPTKDM4E
Hydrochloric Acid SCHEMBL8803047 0.83 NCEH1 (0.53) LDHAKMT2AMEN1MAPTKDM4E
SCHEMBL7776559 0.83 LDHA (0.59) LDHAKMT2AMEN1MAPTKDM4A
SCHEMBL28251208 0.82 LDHA (0.62) LDHAKMT2AMEN1MAPTKDM4A
SCHEMBL29404644 0.82 NCEH1 (0.59) KMT2AMEN1MAPTKDM4ELMNA
SCHEMBL71131 0.82 NCEH1 (0.59) KMT2AMEN1MAPTKDM4ELMNA
SCHEMBL246068 0.82 MAPT (0.52) KMT2AMEN1MAPTKDM4ELMNA
SCHEMBL161927 0.82 MAPT (0.52) LDHAKMT2AMEN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735694-B Method for synthesizing 9-halogen-7H-benzo [ c ] fluorene-7-ketone 西安瑞联新材料股份有限公司 2024-09-13 CN claimed
CN-113735694-A Method for synthesizing 9-halogen-7H-benzo [ c ] fluorene-7-ketone 西安瑞联新材料股份有限公司 2021-12-03 CN claimed
JP-63272584-A None JP disclosed
US-12637414-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-26 US disclosed
US-12630498-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-19 US disclosed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
WO-2026087975-A1 THERMOSENSITIVE RECORDING MEDIUM AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2026-04-30 WO disclosed
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-17 US disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-4676749-A1 THERMOSENSITIVE RECORDING MEDIUM, METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM, AND ARTICLE COMPRISING THE THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2026-01-14 EP disclosed
EP-4679489-A1 TEMPORARY ADHESIVE CONTAINING SILICONE-BASED RESIN, AND PROCESSING METHOD FOR SUBSTRATE WITH CIRCUIT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-01-14 EP disclosed
US-5200385-A Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness RICOH COMPANY, LTD. (JP) 1993-04-06 US disclosed
US-5194418-A A support with a colored layer containing a leuco dye and a dye developer and an overcoating of a crosslinkable resin RICOH COMPANY, LTD. (JP) 1993-03-16 US disclosed
US-5126486-A Color developers for leuco dyes in thermal printing RICOH COMPANY, LTD. (JP) 1992-06-30 US disclosed
US-5043313-A Mixture of leuco dye and diphenyl polyhydroxy sulfone compound RICOH COMPANY, LTD. (JP) 1991-08-27 US disclosed
US-4978651-A With a colorless or light colored leuco dye for inducing color formation RICOH COMPANY, LTD. (JP) 1990-12-18 US disclosed
JP-S63272584-A COLOR REACTION PAPER FOR PRESSURE SENSITIVE PAPER KANZAKI PAPER MFG CO LTD 1988-11-10 JP disclosed
EP-0284359-A1 1,4-Disubstituted piperazine compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-09-28 EP disclosed
US-4521617-A Process for preparing pure alkyl 1-hydroxy-2-naphthoates HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-04 US disclosed
US-3996280-A INTERMEDIATES FOR LOCAL ANESTHETICS AND ARRHYTHMICS RIKER LABORATORIES, INC. (US) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637414-B2 Arylamides and methods of use thereof CFTR, CLIC1, ABCC1 LDHA 4319/4885KMT2A 3177/4885MEN1 4240/4885
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels BHMT, BHMT2, EHMT2 LDHA 2090/4885KMT2A 150/4885MEN1 1478/4885
US-12630498-B2 Arylamides and methods of use thereof CFTR, CLIC1, CLCN2 LDHA 3919/4885KMT2A 3159/4885MEN1 4414/4885
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA LDHA 212/4885KMT2A 3774/4885MEN1 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.