Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190098 | 0.79 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL15855776 | 0.75 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL21066907 | 0.65 | EPHX1 (0.40) | — | |
| SCHEMBL21066905 | 0.65 | EPHX1 (0.40) | — | |
| SCHEMBL23005327 | 0.63 | CHRM2 (0.41) | — | |
| SCHEMBL23005328 | 0.63 | CHRM2 (0.41) | — | |
| SCHEMBL27749154 | 0.63 | NR1I2 (0.35) | NR1I2 | |
| SCHEMBL27880937 | 0.63 | NR1I2 (0.35) | NR1I2 | |
| SCHEMBL7248554 | 0.61 | F10 (0.42) | — | |
| SCHEMBL1700031 | 0.61 | CCR5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026233-B2 | P38 inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2011-09-27 | — | — | US | disclosed |