SCHEMBL24608698

SCHEMBL24608698

Cc1ccc2c(c1)C(=O)c1ccc(C)cc1C21c2ccccc2N2c3ccccc3Sc3cccc1c32

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
BCHE P06276 5/20 0.35
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.33
NOX1 Q9Y5S8 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31
MAPT P10636 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24608701 0.86 NOX1 (0.34) BCHENOX1
SCHEMBL24569263 0.85 NOX1 (0.36) BCHEMEN1KMT2AALDH1A1NOX1
SCHEMBL24608611 0.85 NPC1 (0.39) ALDH1A1
SCHEMBL24608745 0.85 ELANE (0.38) ELANEMEN1KMT2AKDM4EALDH1A1
SCHEMBL24569268 0.84 MEN1 (0.33) BCHEMEN1KMT2AHTTATM
SCHEMBL24608894 0.83 ELANE (0.37) ELANEMEN1KMT2AHTTMAPT
SCHEMBL24608709 0.81
SCHEMBL24608641 0.80 TYMS (0.35) BCHE
SCHEMBL24608706 0.79 BCHE (0.42) BCHEMEN1HPGDKMT2AKDM4E
SCHEMBL27105015 0.79 NPC1 (0.39) BCHEMEN1HPGDKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source CANON KABUSHIKI KAISHA (JP) 2024-02-27 US disclosed
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source CANON KABUSHIKI KAISHA (JP) 2024-02-27 US disclosed
US-20220216423-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source AOX1, SOD1, L1CAM ELANE 757/4885BCHE 2209/4885MEN1 2311/4885
US-20220216423-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE AOX1, SOD1, L1CAM ELANE 757/4885BCHE 2209/4885MEN1 2311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.