SCHEMBL2460883

SCHEMBL2460883

NC(=S)C(CC(=O)O)(C(=O)O)C(N)=S

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ACLY P53396 3/20 0.33
CYP1A2 P05177 1/20 0.33
CPT2 P23786 2/20 0.32
GLRA1 P23415 1/20 0.30
SLC6A9 P48067 1/20 0.30
OR51E2 Q9H255 1/20 0.30
FFAR1 O14842 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23126 0.78 ALDH1A1 (0.53) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL17818674 0.75 ALDH1A1 (0.50) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL11436629 0.75 ALDH1A1 (0.50) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2548829 0.69 CYP2C19 (0.48) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Citric Acid SCHEMBL28667217 0.68 ALDH1A1 (0.71) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL28890751 0.67 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL31635271 0.63 ALDH1A1 (0.43) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL31635270 0.63 ALDH1A1 (0.43) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Citric Acid SCHEMBL8039896 0.63 ALDH1A1 (0.83) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Citric Acid SCHEMBL27872788 0.63 ALDH1A1 (0.83) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550346-A1 ULTRA LOW PHOSPHORUS LUBRICANT COMPOSITIONS R.T. Vanderbilt Company, Inc. (US) 2013-01-30 EP disclosed
WO-2011119918-A1 ULTRA LOW PHOSPHORUS LUBRICANT COMPOSITIONS R.T. VANDERBILT COMPANY, INC. (US) 2011-09-29 WO disclosed