SCHEMBL2460910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2461062	0.91	KDM4E (0.42)	KDM4EMEN1USP2ALDH1A1TP53
	SCHEMBL2464411	0.85	KDM4E (0.42)	KDM4EMEN1USP2ALDH1A1TP53
	SCHEMBL8637498	0.79	POLB (0.41)	KDM4EMEN1ALDH1A1POLBGAA
	SCHEMBL2581752	0.77	CA9 (0.48)	KDM4EMEN1ALDH1A1KMT2ATAS1R3
	SCHEMBL2463055	0.76	MAPT (0.50)	KDM4EMEN1USP2ALDH1A1TP53
	SCHEMBL2460931	0.76	KDM4E (0.50)	KDM4EMEN1USP2ALDH1A1TP53
	SCHEMBL2578379	0.75	HTR2C (0.35)	MEN1POLBMAPTKMT2AHTR2C
	SCHEMBL2578381	0.75	HTR2C (0.35)	MEN1POLBMAPTKMT2AHTR2C
	SCHEMBL2464367	0.74	ALDH1A1 (0.44)	KDM4EMEN1ALDH1A1POLBMAPT
	SCHEMBL11210965	0.74	MAPT (0.64)	KDM4EMEN1USP2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.