SCHEMBL24609656

SCHEMBL24609656

O=C(Nc1ccc(Cl)cc1-c1ccc2nc(-c3ccccc3)ccc2c1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 5/20 0.53
KDM4E B2RXH2 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ADORA3 P0DMS8 1/20 0.48
ADORA1 P30542 2/20 0.46
KCNMA1 Q12791 1/20 0.46
BACE1 P56817 1/20 0.46
CNR1 P21554 1/20 0.45
PLAU P00749 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24609685 0.94 SERPINE1 (0.48) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609579 0.92 SERPINE1 (0.54) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609775 0.91 MEN1 (0.52) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609895 0.88 SERPINE1 (0.48) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609678 0.87 SERPINE1 (0.48) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609587 0.85 MEN1 (0.47) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24610035 0.83 MEN1 (0.53) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL22912465 0.80 SERPINE1 (0.46) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL24609799 0.79 MEN1 (0.47) SERPINE1KDM4ENPSR1RXFP1MEN1
SCHEMBL8980359 0.79 NPC1 (0.69) MEN1KMT2AADORA3ADORA1PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213098-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213098-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 SERPINE1 4369/4885KDM4E 2576/4885NPSR1 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.