Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784800 | 0.78 | MTNR1A (0.37) | GAAMAPT | |
| SCHEMBL2024487 | 0.76 | MAPT (0.43) | GAAMAPTARBRD4CREBBP | |
| SCHEMBL30059612 | 0.72 | MAPT (0.53) | GAAMAPTARBRD4CREBBP | |
| SCHEMBL13784855 | 0.71 | GAA (0.32) | GAAMAPT | |
| SCHEMBL14011740 | 0.71 | HTR2A (0.33) | GAAMAPT | |
| SCHEMBL23637643 | 0.70 | CREBBP (0.31) | BRD4CREBBP | |
| SCHEMBL18068338 | 0.69 | GAA (0.40) | GAAMAPTARBRD4CREBBP | |
| SCHEMBL22361781 | 0.68 | IDO1 (0.48) | — | |
| SCHEMBL26054011 | 0.67 | GAA (0.38) | GAAMAPTARBRD4CREBBP | |
| SCHEMBL12475851 | 0.66 | GAA (0.47) | GAAMAPTARBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347355-B1 | HETEROTRICYCLIC SULFONAMIDES AS ANTI-CANCER AGENTS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2022-07-13 | — | — | EP | disclosed |