Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682225 | 0.84 | MAPK1 (0.64) | MAPK1SMN1; SMN2GLAKMT2ARXFP1 | |
| SCHEMBL18819561 | 0.82 | KMT2A (0.41) | MAPK1POLBHIF1ASMN1; SMN2HTT | |
| SCHEMBL18819717 | 0.82 | TRPA1 (0.41) | POLBHIF1AKMT2ARXFP1TRPA1 | |
| SCHEMBL17682183 | 0.80 | TRPA1 (0.42) | POLBHIF1AKMT2ATRPA1ABCC8 | |
| SCHEMBL17682175 | 0.80 | KMT2A (0.42) | MAPK1POLBHIF1ASMN1; SMN2HTT | |
| SCHEMBL19607719 | 0.78 | KMT2A (0.43) | KMT2ARXFP1ADORA2BTRPA1ABCC8 | |
| SCHEMBL18819720 | 0.78 | TRPA1 (0.42) | POLBHIF1AKMT2ARXFP1TRPA1 | |
| SCHEMBL19607601 | 0.78 | KMT2A (0.44) | POLBHIF1AKMT2ARXFP1TRPA1 | |
| SCHEMBL18819085 | 0.78 | TRPA1 (0.43) | HTTKMT2ARXFP1TRPA1 | |
| SCHEMBL24611641 | 0.77 | KMT2A (0.43) | KMT2ARXFP1ADORA2BTRPA1ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |