Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 15/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682257 | 0.83 | ADORA2B (0.47) | KMT2ARXFP1 | |
| SCHEMBL18819720 | 0.82 | TRPA1 (0.42) | TRPA1KMT2ARXFP1 | |
| SCHEMBL18819561 | 0.82 | KMT2A (0.41) | TRPA1KMT2AHTTRXFP1 | |
| SCHEMBL20182665 | 0.81 | TRPA1 (0.44) | TRPA1KMT2AHTTRXFP1PARG | |
| SCHEMBL19607601 | 0.81 | KMT2A (0.44) | TRPA1KMT2ARXFP1 | |
| SCHEMBL18819630 | 0.79 | KMT2A (0.42) | TRPA1KMT2ARXFP1 | |
| SCHEMBL18819717 | 0.78 | TRPA1 (0.41) | TRPA1KMT2ARXFP1 | |
| SCHEMBL17682175 | 0.78 | KMT2A (0.42) | TRPA1KMT2AHTTRXFP1 | |
| SCHEMBL24611642 | 0.78 | MAPK1 (0.46) | TRPA1KMT2AHTTRXFP1 | |
| SCHEMBL24611641 | 0.78 | KMT2A (0.43) | TRPA1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |