Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.53 |
| ▸ | CCKAR | P32238 | 10/20 | 0.53 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.44 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.44 |
| ▸ | RBPJ | Q06330 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867036 | 1.00 | CCKBR (0.53) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24611948 | 0.88 | CCKBR (0.56) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL20867269 | 0.88 | CCKBR (0.51) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867180 | 0.88 | CCKBR (0.50) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20866850 | 0.87 | CCKBR (0.48) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24612077 | 0.87 | CCKBR (0.48) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24611978 | 0.87 | CCKBR (0.54) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL20866842 | 0.87 | CCKBR (0.54) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL20866910 | 0.86 | CCKAR (0.49) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24612036 | 0.86 | CCKBR (0.53) | CCKBRCCKARNOTCH1RBPJ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |