Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890712 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HDAC1KMT2AAOC3PKM | |
| SCHEMBL14929989 | 0.81 | HDAC1 (0.41) | ALDH1A1HDAC1KMT2AAOC3PKM | |
| SCHEMBL8629375 | 0.80 | TDP1 (0.45) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL10351167 | 0.79 | DPP4 (0.50) | ALDH1A1KMT2AAOC3MEN1MAPT | |
| SCHEMBL9055270 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2APKMPOLBHPGD | |
| SCHEMBL8918321 | 0.76 | KMT2A (0.37) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL25949962 | 0.75 | CYP3A4 (0.50) | ALDH1A1HDAC1KMT2AAOC3PKM | |
| SCHEMBL27270811 | 0.75 | HDAC1 (0.46) | ALDH1A1HDAC1KMT2AAOC3PKM | |
| SCHEMBL10435223 | 0.75 | CYP3A4 (0.50) | ALDH1A1HDAC1KMT2AAOC3PKM | |
| SCHEMBL1430200 | 0.75 | KMT2A (0.48) | ALDH1A1KMT2ACA4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728191-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-13 | — | — | EP | disclosed |